Antibiotics damage the gut microbiome, which can result in overgrowth of pathogenic microorganisms and emergence of antibiotic resistance.Inactivation of antibiotics in the small intestine represents a novel strategy to protect the colonic microbiota.SYN-004 (ribaxamase) is a beta-lactamase formulated for oral delivery intended to degrade intraveno
There are inconsistent and limited data regarding the risk of myeloid neoplasms (MN) among breast cancer survivors who received radiotherapy (RT) in the absence of chemotherapy.Concern about subsequent MN might influence the decision to use adjuvant RT for women with localized disease.As patients with therapy-related MN have generally poor outcomes
Summary: Non-small-cell lung cancer remains a deadly form of human cancer even in the era of immunotherapy with existing immunotherapy strategies currently only benefiting a minority of patients.Therefore, the derivation of treatment options, which might extend the promise of immunotherapy to more patients, remains of paramount importance.Here, we
Abstract Photodynamic therapy (PDT) as a clinical method relies on appropriate light delivery to activate photosensitizers, usually necessitates the utilization of cumbersome surgical instruments and high irradiation intensity, along with the requirement for hospitalization.To extend the applicability of PDT beyond hospital for better patient mobil